SCORE2 calculator: 10-year cardiovascular disease risk

SCORE2 is the European Society of Cardiology’s current tool for the 10-year risk of cardiovascular events (heart attack, stroke) in people aged 40–89 without established heart disease. Enter age, sex, blood pressure, cholesterol, smoking and diabetes — the calculator computes risk calibrated to a region (default “very high”, which includes Russia) and for 70+ automatically applies the SCORE2-OP version.

Estimate cardiovascular risk (SCORE2)

Sex

Fill in sex, age, blood pressure and cholesterol — the risk appears instantly.

SCORE2 risk categories (age-dependent)

ESC low/moderate/high thresholds differ by age: the same percentage is more concerning when younger. The final prevention decision is made by a doctor.

AgeLow · moderate · high
40–49 years< 2.5% · 2.5–7.5% · ≥ 7.5%
50–69 years< 5% · 5–10% · ≥ 10%
70–89 years< 7.5% · 7.5–15% · ≥ 15%

What SCORE2 is

SCORE2 (Systematic COronary Risk Evaluation 2) is a 2021 model estimating the probability of a fatal or non-fatal cardiovascular event (heart attack, stroke) over the next 10 years. It replaced the older SCORE because it also counts non-fatal events and is recalibrated to modern data.

It is for apparently healthy people aged 40–89 — without established coronary disease, prior heart attack or stroke, diabetes with organ damage, severe kidney disease or familial hypercholesterolemia (whose risk is high by default).

How it works and why region matters

It uses age, sex, smoking, systolic (upper) blood pressure, total and HDL cholesterol, and diabetes. Cholesterol is entered in mmol / L.

Absolute risk depends on how common cardiovascular disease is in the country. Europe is split into 4 regions (low, moderate, high, very high); Russia is in the “very high” risk region — the default. You can change the region under “Refine”.

SCORE2-OP for age 70 and above

In older people the standard SCORE2 would overestimate risk, so a separate version — SCORE2-OP (Older Persons) — was developed for ages 70–89. The calculator picks the right model by age automatically.

Why thresholds depend on age

The same risk percentage means different things at different ages. For example, 6% at 45 is already a high relative risk (harm came early), while at 65 the same 6% is moderate. So the ESC uses different thresholds for 40–49, 50–69 and 70–89 — the calculator shows the category for your age.

What to do with the result

High and moderate risk is a reason to discuss lifestyle and, if needed, lowering cholesterol and blood pressure with your doctor. Low risk does not cancel healthy habits. SCORE2 supports a prevention decision but is not a diagnosis.

The result is an estimate, not a verdict: factors not in the model (heredity, obesity, inactivity) also matter. A doctor sets the exact plan.

Frequently asked questions

  • Enter age, sex, smoking, upper (systolic) blood pressure, total and HDL cholesterol (in mmol / L) and mark diabetes. The calculator computes the 10-year risk of heart attack/stroke calibrated to Russia’s region and shows the category for your age.

  • Thresholds depend on age: at 40–49 high is from 7.5%, at 50–69 from 10%, at 70–89 from 15%. Moderate and high risk is a reason to discuss prevention with a doctor.

  • SCORE estimated only fatal events; SCORE2 (2021) also counts non-fatal ones (heart attack, stroke), is recalibrated to modern data and split by risk region. For 70+ there is the SCORE2-OP version.

  • Cardiovascular disease rates differ between countries, so the same profile gives a different absolute risk. Russia is in the “very high” risk region — the default; other regions can be chosen under “Refine”.

  • People who already have heart disease, a prior heart attack/stroke, diabetes with organ damage, severe kidney disease or familial hypercholesterolemia — their risk is high by definition and a doctor sets the plan directly.

Cholesterol and glucose — values from your blood test

Upload your report — AI reads lipids and glucose together, links them to blood pressure and suggests what to discuss with your doctor.

Decode my lab results

This calculator is for reference and information only and is not a diagnosis. Risk assessment and prevention are determined by a doctor.